Name
Jing Han, Department of Occupational and Environmental Health, School of Public Health, Xi 'an Jiaotong University, Professor, Doctoral Tutor
Research Field (Direction)
1. Pathogenesis of bone and cartilage diseases with protein and glycoproteomics.
2. Preparation and biological evaluation of cartilage repair materials.
3. Identification of occupational harmful factors and health promotion of occupational population (mechanism and protection)
4. The relationship between environmental pollutants (PAHs, heavy metal elements and PM2.5, etc.) and chronic diseases
5. Research on the healthy growth of adolescents (physical, psychological, learning ability, career planning, etc.)
Educational Background
2009.09-2013.10 School of Public Health, Xi'an Jiaotong University, Doctor of Medicine
2006.09-2009.07 Biomedical Engineering Research Center, Xiamen University, Master of Science
2001.09-2005.07 School of pharmaceutical science, Xi'an Jiaotong University, Bachelor of Science and Economics
Work Experience
2024.01-now Department of Occupational and Environmental Health, School of Public Health, Xi'an Jiaotong University, Professor
2020.11-2021.10 The High School Affiliated to Xi 'an Jiaotong University (Yanta campus), Vice Principal(serve temporary position)
2019.04-2021.04 School of Public Health, Xi 'an Jiaotong University, Department of Occupational and Environmental Health, Deputy Head (in charge)
2016.12-2023.12 Department of Occupational and Environmental Health, School of Public Health, Xi'an Jiaotong University, Associate Professor
2015.09-2016.09 Department of Biomaterial, School of Mechanical Engineering, National University of Singapore, Visiting Scholar
2013.11-2017.04 Department of Material Processing Engineering, School of Materials, Xi'an Jiaotong University, Postdoctoral researcher
2013.11-2016.12 Department of Occupational and Environmental Health, School of Public Health, Xi'an Jiaotong University, Lecturer
2011.08-2011.11 School of Life Sciences, University of Eastern Finland, Visiting Scholar
2005.07-2006.09 Shaanxi University of Chinese Medicine, Teacher
Teaching and research results, patents, papers
Since 2013, I have been granted 19 fund projectsand received a total of over 4.0 million Yuan. Up to now, I have published 85 academic papers, including 61 pieces of SCI papers (42 pieces of SCI papers were published as first author/only correspondence author), 7 pieces of papers in Chinese core journals as first/correspondence author. I have applied six invention patents (four items were authorized), and authorized one utility model patent. I have been awarded the third prize of Science and Technology of Shaanxi Province (first completer), the second prize of the 2023 Invention and Entrepreneurship Award (first completer), the Person Award of the 13th Invention and Entrepreneurship Award of 2023, the second prize of science and technology of Shaanxi Province Higher Education Institution (first completer), the Science and Technology Award of Shaanxi Province for Environmental Protection (fourth completer), award for doctoral students and 7th Edition of International Research Best Researcher Award. In 2023, it was selected into the first Public Health High-level Talent Training Program of Chinese Preventive Medical Association. Currently, I have been the chief expert of the research team on health risks, effects and prevention and control of exposure to novel environmental pollutants, served as a provincial occupational health expert in Shaanxi Province, a member of council of Medicine Association Shaanxi Preventive, Standing Committee of the Occupational, Environmental and Occupational Disease Branch of Xi'an Medical Association, and Committee on the Promotion of Endemic Diseases in Health Promotion Association in Shaanxi Province, and Nutrition and Food Safety Professional Committee of Preventive Medicine Association in Shaanxi Province. I have participated in the compilation of Famine Starvation and Nutrient Deprivation From Biology to Policy and Fundamentals and Applications of Molecular Biology of Endemic Diseases (editorial member). Served as youth editorial board member of Hygiene and Environmental Health Advances and guest editor of Nutrients.
Major research projects
1. Xi'an Evidence-based Pharmaceutical Technology Co., Ltd, 2311208, EEOD Team Development Fund, Funding of 1 million Yuan, From 2023/01/01 to 2033/12/31, In charge
2. National Natural Science Foundation of China, "The molecular mechanism of mTOR signal pathway and mitochondria-endoplasmic reticulum autophagy in chondrocyte damage with Kashin-Beck disease", Project number 81872567, Funding of 570,000 Yuan, From 2019/01/01 to 2022/12/31, In charge
3. The National Natural Science Foundation of China Youth Science Foundation Project, "The role of abnormal chondroitin sulfate biosynthesis and catabolism in the cartilage damage of Kashin-Beck Disease", Funding of 230,000 Yuan, Project number 81402639, From 2015/01/01 to now , In charge
4. Project of Shaanxi Provincial Academy of Environmental Sciences, "China's Capacity Building Project for the Implementation of the Minamata Convention on Mercury (three bids)", Project number 202012257, Funding of 978,000 Yuan, From 2021/01/01 to now, In charge
5. Project of South China Institute of Environmental Sciences, Ministry of Ecology and Environment, "Environment and Health Risk Sentinel Monitoring of an Industrial Park in Shaanxi-Population Health Monitoring", Project number 21111011101EHSM-SXSM-02, Total funding of 380,000 Yuan, From 2019/06/14 to 2020/12/31, In charge
Representative Papers (* Corresponding author)
1. Han Jing#,*, Deng Huan#, Li Yang#, Qiao Lichun, Jia Hongrui, Zhang Lan, Wang Linghang, Qu Chengjuan. Nano-elemental selenium particle developed via supramolecular self-assembly of chondroitin sulfate A and Na2SeO3 to repair cartilage lesions. Carbohydrate Polymers, 2023, 316:121047.
2. Han Jing, Guo Xiong, Lei Yanxia, Dennis Bannel S., Wu Shixun, Wu Cuiyan. Synthesis and characterization of selenium-chondroitin sulfate nanoparticles. Carbohydrate Polymers. 2012, 90: 122-126.
3. Hou Z, Han J, Zhan C, et al. Synthesis and evaluation of N-succinyl-chitosan nanoparticles toward local hydroxycamptothecin delivery. Carbohydrate Polymers, 2010, 81(4):765-768.
4. Ding Tiexin, Liu Fuwei, Xin He, Chen Yicheng, Kong Liang, Han Jing, Ma Dayan, Han Yong, Zhang Lan. Pyro-piezoelectric effect of BaTiO3 bio-nanocarrier for osteomyelitis therapy. Nano today. 2024, 102069.
5. Ding Tiexin, Zhang Lan*, Han Jing, Zhou Jianhong, Han Yong*. Photo-Responded Antibacterial Therapy of Reinfection in Percutaneous Implants by Nanostructured Bio-Heterojunction. Small. 2023, 19(7), e2206265.
6. Lyu Yizhen#, Deng Huan#, Qu chengjuan#, Qiao Lichun, Liu Xuan, Xiao Xiang, Liu Jiaxin, Guo Ziwei, Zhao Yan, Han Jing*, Lammi Mikko J. Identification of proteins and N-glycosylation sites of knee cartilage in Kashin-Beck Disease compared with osteoarthritis. International Journal of Biological Macromolecules. 2022, 210:128-138.
7. Han Jing#*, Deng Huan#, Lyu Yizhen, Xiao Xiang, Zhao Yan, Liu Jiaxin, Guo Ziwei, Liu Xuan, Qiao Lichun, Lammi Mikko Juhani*. Identification of N-Glycoproteins of knee cartilage from adult osteoarthritis and Kashin-Beck disease based on quantitative glycoproteomics, compared with normal control cartilage. Cells. 2022,11(16):2513.
8. Qiao Lichun#, Lin Xue#, Liu Haobiao#, Xiang Rongqi, Zhan Jingming, Deng Feidan, Bao Miaoye, He Huifang, Wen Xinyue, Deng Huan, Wang Xining, He Yujie, Yang Zhihao, Han Jing*. T-2 toxin induces cardiac fibrosis by causing metabolic disorders and up-regulating Sirt3/FoxO3α/MnSOD signaling pathway-mediated oxidative stress. Journal of Environmental Sciences. 2024
9. Liu Haobiao#, Lin Xue#, Chilufya Mumba Mulutula#, Qiao Lichun, Bao Miaoye, Wen Xinyue, Xiang Rongqi, He Huifang, Li Miaoqian, Han Jing*. Synergistic effects of T-2 toxin and selenium deficiency exacerbate renal fibrosis through modulation of the ERα/PI3K/Akt signaling pathway. Ecotoxicology and Environmental Safety. 2024, 269:115748.
10. Qiao Lichun#, Guo Ziwei#, Liu Haobiao#, Liu Jiaxin, Lin Xue, Deng Huan, Liu Xuan, Zhao Yan, Xiao Xiang, Lei Jian, Han Jing*. Protective effect of mitophagy regulated by mTOR signaling pathway in liver fibrosis associated with selenium. Nutrients. 2022,14(12):2410.
11. Xiao Xiang, Deng Huan, Lin Xue, Ali Ahmed Sameir Mohamed, Viscardi Angelo, Guo Ziwei, Qiao Lichun, He Yujie, Han Jing*. Selenium nanoparticles: Properties, preparation methods, and therapeutic applications. Chemico-Biological Interactions. 2023, 378:110483.
12. Liu Jiaxin#, Li Hongqiu#, Guo Ziwei, Xiang Xiao, Angelo Viscardi, Rongqi Xiang, Haobiao Liu, Xue Lin, Han Jing*. The Changes and Correlation of IL-6 and Oxidative Stress Levels in RAW264.7 Macrophage Cells Induced by PAHs in PM2.5. Environmental Geochemistry and Health. 2023.
13. Zhao Yan#, Sheng Yun#, Zhou Jieting#, Wang Hao, Chilufya Mumba Mulutula, Liu Xuan, Mohamed Alaa Osman, Han Jing*, Qu Chenjuan. Influencing factors of residents' environmental health literacy in Shaanxi province, China: a cross-sectional study. BMC Public Health. 2022, 22(1):114.
14. Qiao Lichun#, Liu Xuan#, He Yujie#, Zhang Jiaheng, Huang Hao, Bian Wenming, Chilufya Mumba Mulutula, Zhao Yan, Han Jing*. Progress of signaling pathways, stress pathways, and epigenetics in the pathogenesis of skeletal fluorosis. International Journal of Molecular Sciences. 2021, 21(22): 11932.
Contact information
E-mail: bbbishop@126.com
Contact number: 029-82655106
Contact Address: School of Public Health, Health Science Center, Xi 'an Jiaotong University
