罗小琴

罗小琴，女，营养与食品安全系副教授。2007 年毕业于兰州大学预防医学专业，2012 年 7 月获得中山大学公共卫生学院博士学位，毕业后进入西安交通大学公共卫生学院开始工作。同时进入西安交通大学心血管研究中心进行博士后工作。2015 年 8 月至 2016 年 8 月，澳大利亚昆士兰大学 Mater 研究中心访问学者。博士毕业后一直从事营养与食品卫生学的教学和研究工作。主要研究方向为：营养与慢性代谢性疾病的防治，曾参与《植物花色苷》和《肿瘤营养学》两部著作；并先后主持承担国家及部级科研项目等，在国内外发表科研论文数篇，其中 SCI 收录论文 17 篇。

科研成果

近年来发表与本课题相关的SCI 论文及专著：

[1]

[1] Luo Xiaoqin, Jia Ru, Yao Qinyu, Xu Yirui, Luo Zhenyu, Lei Xiao, Wang Nanping. Docosahexaenoic acid attenuates adipose tissue angiogenesis and insulin resistance in high fat diet-fed middle-aged mice via a sirt1-dependent mechanism. Molecular Nutrtion and Food Research. 2016; 60(4):871-885.

[2] Luo Xiaoqin, Luo Zhenyu, Zhang Zihui, Yang Haixia, Lai Bei, Yao Qinyu, Xiao Lei, Wang Nanping. Homocysteine upregulates hepcidin expression through BMP6/SMAD signaling pathway in hepatocytes. Biochemical and Biophysical Research Communications. 2016; 471(2):303-308.

[3] Luo Xiaoqin, Xiao Lei, Yang Haixia, Zhang Ruijuan, Jiang Manli, Ni Jiahua, Lei Ting, Wang Nanping. Homocysteine downregulates gene expression of heme oxygenase-1 in hepatocytes. Nutrition & Metabolism (Lond). 2014;11(1):55.

[4] Zhang Ruijuan, Yu Yan, Hu Senke, Zhang Jinghua, Yang Haixia, Han Bei, Cheng Yue, Luo Xiaoqin. Sesamin ameliorates hepatic steatosis and inflammation in rats on a high-fat diet via LXRα and PPARα. Nutrition Research. 2016; 36 (9):1022-1030 (通讯作者)

[5] Luo Xiaoqin, Xiao Yunjun, Song Fenglin, Yang Yan, Xia Min, Ling Wenhua. Increased plasma S-adenosyl-homocysteine levels induce VSMCs proliferation and migration through an oxidative stress-dependent activation of the ERK1/2 pathway to promote atherogenesis in apolipoprotein E-deficient mice. Cardiovascular Research. 2012.94:2

[6] Luo Xiaoqin, Fang Shi, Xiao Yunjun, Song Fenglin, Zou Tangbin, Wang Min, Xia Min, Ling Wenhua. Cyanidin-3- glucoside suppresses TNF-alpha-induced cell proliferation through the repression of Nox activator 1 in mouse vascular smooth muscle cells: involvement of the STAT3 signaling. Mol Cell Biochem. 2012;362:211-218.

[7] Luo Xiaoqin, Yang Yan, Shen Tianran, Tang Xilan, Zou Tangbin, Xia Min, Ling Wenhua. Docosahexaenoic acid ameliorates palmitic acid-induced steatohepatitis through repressing NLRC4 inflammasome activation in HepG2 cells. Nutrition and Metabolism. 2012.9:34

[8] Jia Ru, Luo Xiaoqin, Wang G, Lin CX, Qiao H, Wang N, Yao T, Barclay JL, Whitehead JP, Luo Xiao and Yan Jianqun. Characterization of cold-induced remodelling reveals depot-specific differences across and within brown and white adipose tissues in mice. Acta Physiologica 2016;217(4):311-324.

[9] Xiao Lei, Zhang Zihui, Luo Xiaoqin, Yang Haixia, Li Fan, Wang Nanping. Retinoid acid receptor-related orphan receptor alpha (RORα) regulates macrophage M2 polarization via activation of AMPKα. Mol Immunol. 2016;24(80):17-23.

[10] Zhang Ruijuan, Yu Yan, Deng Jianjun, Zhang Chao, Zhang Jie, Cheng Yue, Luo Xiaoqin, Han Bei, Yang Haixia. Sesamin Ameliorates High-Fat Diet-Induced Dyslipidemia and Kidney Injury by Reducing Oxidative Stress. Nutrients. 2016;8(5).

[11] Ni Jiahua, Zhang Zihui, Luo Xiaoqin, Xiao Lei, Wang Nanping. Plasticizer DBP Activates NLRP3 Inflammasome through the P2X7 Receptor in HepG2 and L02 Cells. J Biochem Mol Toxicol. 2016;30(4):178-85.

[12] Ji Jinshan, Zhang Chao, Luo Xiaoqin, Wang Li, Zhang Ruijuan, Wang Zhenlin, Fan Daidi, Yang Haixia, Deng Jianjun. Effect of Stay-Green Wheat, a Novel Variety of Wheat in China, on Glucose and Lipid Metabolism in High-Fat Diet Induced Type 2 Diabetic Rats. Nutrients. 2015;7(7):5143-55.

[13] Yang Haixia, Xiao Lei, Yuan Yue, Luo Xiaoqin, Jiang Manli, Ni Jiahua, Wang Nanping. Procyanidin B2 inhibits NLRP3 inflammasome activation in human vascular endothelial cells. Biochem Pharmacol. 2014; 92(4):599-606

[14] Xiao Lei, Zhang Zihui, Luo Xiaoqin. Roles of xenobiotic receptors in vascular athophysiology. Circ J. 2014;78(7):1520-1530.

[15] Zou Tangbin, Wang Dongliang, Guo Honghui, Zhu Yanna, Luo Xiaoqin, Liu Fengqiong, Ling Wenhua. Optimization of microwave-assisted extraction of anthocyanins from mulberry and identification of anthocyanins in extract using HPLC-ESI-MS. J Food Sci.2012;77:C46-50.

[16] Xiaofei Lv, Yuan Zhang, Shaoqi Rao, Jian Qiu, Min Wang, Luo Xiaoqin, Xiaoyu Zuo, Dongfang Su, Xiang Feng, Yan Yang, Ping Ouyang, Yibing Chen, Xinrui Li, Yunjun Xiao, Wenhua Ling. Joint effects of genetic variants in multiple loci on the risk of coronary artery disease in Chinese Hans. Circ J. 2012;76(8):1987-1992.

[17] Yin Yi，Yu Zhiwen, Xia Min, Luo Xiaoqin, Lv Xiaofei and Ling Wenhua. Vitamin D Attenuates High Fat Diet-induced Hepatic Steatosis in Rats by Modulating Lipid Metabolism. Eur J Clin Invest. 2012;42(11):1189-1196.

[18] 冯丹，朱艳娜，王冬亮，尹逸，罗小琴，陈维清，凌文华. 番茄红素对脂多糖诱导巨噬细胞炎症反应的影响. 中国公共卫生

承担科研项目情况

通信地址
西安交通大学公共卫生学院营养系 710061
电 话 029-82655101
E-mail luoxiaoqin2012@mail.xjtu.edu.cn